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Gene id 79799
Gene Summary    Protein Summary    Gene ontology    KEGG pathways    Diseases    PubMed    

Gene Summary

Gene Symbol UGT2A3   Gene   UCSC   Ensembl
Gene name UDP glucuronosyltransferase family 2 member A3
Alternate names UDP-glucuronosyltransferase 2A3, UDP glucuronosyltransferase 2 family, polypeptide A3, UDPGT 2A3,
Gene location 4q13.2 (68951803: 68928459)     Exons: 7     NC_000004.12
OMIM 605948

Protein Summary

Protein general information Q6UWM9  

Name: UDP glucuronosyltransferase 2A3 (UDPGT 2A3) (EC 2.4.1.17)

Length: 527  Mass: 60254

Sequence MRSDKSALVFLLLQLFCVGCGFCGKVLVWPCDMSHWLNVKVILEELIVRGHEVTVLTHSKPSLIDYRKPSALKFE
VVHMPQDRTEENEIFVDLALNVLPGLSTWQSVIKLNDFFVEIRGTLKMMCESFIYNQTLMKKLQETNYDVMLIDP
VIPCGDLMAELLAVPFVLTLRISVGGNMERSCGKLPAPLSYVPVPMTGLTDRMTFLERVKNSMLSVLFHFWIQDY
DYHFWEEFYSKALGRPTTLCETVGKAEIWLIRTYWDFEFPQPYQPNFEFVGGLHCKPAKALPKEMENFVQSSGED
GIVVFSLGSLFQNVTEEKANIIASALAQIPQKVLWRYKGKKPSTLGANTRLYDWIPQNDLLGHPKTKAFITHGGM
NGIYEAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAVEINFKTMTSEDLLRALRTVITDSSYKENAMRLSRIHHDQ
PVKPLDRAVFWIEFVMRHKGAKHLRSAAHDLTWFQHYSIDVIGFLLACVATAIFLFTKCFLFSCQKFNKTRKIEK
RE
Structural information
Interpro:  IPR002213  IPR035595  
Prosite:   PS00375
MINT:  
STRING:   ENSP00000251566
Other Databases GeneCards:  UGT2A3  Malacards:  UGT2A3

Gene ontology

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GO accessionTerm nameEvidence codeGo category
GO:0043231 intracellular membrane-bo
unded organelle
IBA cellular component
GO:0008194 UDP-glycosyltransferase a
ctivity
IBA molecular function
GO:0015020 glucuronosyltransferase a
ctivity
IDA molecular function
GO:0008194 UDP-glycosyltransferase a
ctivity
IEA molecular function
GO:0016740 transferase activity
IEA molecular function
GO:0016020 membrane
IEA cellular component
GO:0016021 integral component of mem
brane
IEA cellular component
GO:0016757 transferase activity, tra
nsferring glycosyl groups
IEA molecular function
GO:0015020 glucuronosyltransferase a
ctivity
IEA molecular function
GO:0052695 cellular glucuronidation
IDA biological process
GO:0016020 membrane
IEA cellular component
GO:0043231 intracellular membrane-bo
unded organelle
IBA cellular component
GO:0008194 UDP-glycosyltransferase a
ctivity
IBA molecular function
GO:0015020 glucuronosyltransferase a
ctivity
IDA molecular function
GO:0008194 UDP-glycosyltransferase a
ctivity
IEA molecular function
GO:0016740 transferase activity
IEA molecular function
GO:0016020 membrane
IEA cellular component
GO:0016021 integral component of mem
brane
IEA cellular component
GO:0016757 transferase activity, tra
nsferring glycosyl groups
IEA molecular function
GO:0015020 glucuronosyltransferase a
ctivity
IEA molecular function
GO:0052695 cellular glucuronidation
IDA biological process
GO:0016020 membrane
IEA cellular component

KEGG pathways

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Pathway idPathway name
hsa01100Metabolic pathways
hsa00983Drug metabolism - other enzymes
hsa05204Chemical carcinogenesis
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00982Drug metabolism - cytochrome P450
hsa00830Retinol metabolism
hsa00140Steroid hormone biosynthesis
hsa00860Porphyrin and chlorophyll metabolism
hsa00040Pentose and glucuronate interconversions
hsa00053Ascorbate and aldarate metabolism
Associated diseases References
Aberrant CpGs in Low Motility Sperm MIK: 21674046

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
21674046 Aberrant C
pGs in Low
Motility
Sperm

18
Male infertility GSE26881
Show abstract