• Gene id: 79758

Gene Summary

• Gene Symbol: DHRS12   Gene   UCSC   Ensembl
• Aliases: SDR40C1
• Gene name: dehydrogenase/reductase 12
• Alternate names: dehydrogenase/reductase SDR family member 12, dehydrogenase/reductase (SDR family) member 12, short-chain dehydrogenase/reductase family 40C member 1,
• Gene location: 13q14.3 (204545474: 205620161)     Exons: 33     NC_000002.12
• Gene summary(Entrez): This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members in this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids a
• OMIM: 616163

Protein Summary

• Protein general information: A0PJE2  
  • Name: Dehydrogenase/reductase SDR family member 12 (EC 1.1. . ) (Short chain dehydrogenase/reductase family 40C member 1)
  • Length: 317  
  • Mass: 35146
• Sequence:

  MSLYRSVVWFAKGLREYTKSGYESACKDFVPHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQA
  PAEDARGEIIRESGNQNIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLG
  VYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFS
  SMHPGWADTPGVRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQDRKPVSTHLPLATASSSPA
  EEEKLIEILEQLAQTFK

• Structural information:
  • Interpro: IPR036291  IPR002347  
  • STRING: ENSP00000411565
• Other Databases: GeneCards:  DHRS12  Malacards:  DHRS12

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0055114	oxidation-reduction process	IEA	biological process
GO:0016491	oxidoreductase activity	IEA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)