• Gene id: 79750

Gene Summary

• Gene Symbol: ZNF385D   Gene   UCSC   Ensembl
• Aliases: ZNF659
• Gene name: zinc finger protein 385D
• Alternate names: zinc finger protein 385D, zinc finger protein 659,
• Gene location: 3p24.3 (67430401: 67407809)     Exons: 8     NC_000001.11

Protein Summary

• Protein general information: Q9H6B1  
  • Name: Zinc finger protein 385D (Zinc finger protein 659)
  • Length: 395  
  • Mass: 42296
• Sequence:

  MRNIMYFGGTCQSPALPALVRPPAPPLQPSLDIKPFLPFPLDTAAAVNLFPNFNAMDPIQKAVINHTFGVPLPHR
  RKQIISCNICQLRFNSDSQAAAHYKGTKHAKKLKALEAMKNKQKSVTAKDSAKTTFTSITTNTINTSSDKTDGTA
  GTPAISTTTTVEIRKSSVMTTEITSKVEKSPTTATGNSSCPSTETEEEKAKRLLYCSLCKVAVNSASQLEAHNSG
  TKHKTMLEARNGSGTIKAFPRAGVKGKGPVNKGNTGLQNKTFHCEICDVHVNSETQLKQHISSRRHKDRAAGKPP
  KPKYSPYNKLQKTAHPLGVKLVFSKEPSKPLAPRILPNPLAAAAAAAAVAVSSPFSLRTAPAATLFQTSALPPAL
  LRPAPGPIRTAHTPVLFAPY

• Structural information:
  • Interpro: IPR003604  IPR036236  IPR013087  
  • STRING: ENSP00000281523
• Other Databases: GeneCards:  ZNF385D  Malacards:  ZNF385D

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0008270	zinc ion binding	IEA	molecular function
GO:0003676	nucleic acid binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R