• Gene id: 79613

Gene Summary

• Gene Symbol: TANGO6   Gene   UCSC   Ensembl
• Aliases: TMCO7
• Gene name: transport and golgi organization 6 homolog
• Alternate names: transport and Golgi organization protein 6 homolog, transmembrane and coiled-coil domain-containing protein 7, transmembrane and coiled-coil domains 7,
• Gene location: 16q22.1 (68843530: 69085181)     Exons: 19     NC_000016.10
• OMIM: 616506

Protein Summary

• Protein general information: Q9C0B7  
  • Name: Transport and Golgi organization protein 6 homolog (Transmembrane and coiled coil domain containing protein 7)
  • Length: 1094  
  • Mass: 120748
• Sequence:

  MAARQAVGSGAQETCGLDRILEALKLLLSPGGSGSSSLQVTKHDVLLATLKSNLSALEDKFLKDPQWKNLKLLRD
  EIADKAEWPQNSVDVTWSFTSQTLLLLLCLKETMIRLAANFNPGKPNPRTPEVAPALSPDALSISQQKTVQFVLQ
  FVVTLGICPYLMPGVGVPLRYRTEFGAVVQDVVCFDAAPDATRRLYTSCKALLNVAQHTSLGSLIFCHHFGDIAA
  GLCQLGFCPTKRKLLTPAEEVLTEEERTLSRGALRDMLDQVYQPLAVRELLILQGGPPQSCTDVKTQMRCRAPAW
  LRRLCGQLLSERLMRPNGVQAVVRGILEGAGAGAAGGSDAEVTAADWKKCDLIAKILASCPQQSLSPENYYRDIC
  PQVLDLFHFQDKLTARQFQRVATTTFITLSRERPHLAAKYLLQPVLAPLHRCLNTAELSESDMVPGTILVTEEEL
  SRCIEDVFKVYVVGNEPLTVLMDSLLPVLGVLFLLYCFTKQSVSHIRSLCQEILLWILGKLERKKAIASLKGFAG
  LDKAVPSLHSLCQFRVATQGGIMITIKEAISDEDEDEALYQKVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLK
  ELTHVASENETELKTEPFSSKSLLELEQHQTLLVEGQERKLLVLQLMAVLCERMSEQIFTNVTQVVDFVAATLQR
  ACASLAHQAESTVESQTLSMSMGLVAVMLGGAVQLKSSDFAVLKQLLPLLEKVSNTYPDPVIQELAVDLRITIST
  HGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPST
  TTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQ
  GVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGAHRA
  SSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLK
  HVVCLEPDDVAKLHAQLALEELDDIMKNFLFPPQKLEKKIMVLP

• Structural information:
  • Interpro: IPR011989  IPR016024  IPR019451  IPR019414  IPR039600  
  • STRING: ENSP00000261778
• Other Databases: GeneCards:  TANGO6  Malacards:  TANGO6

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0009306	protein secretion	IBA	biological process
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq