• Gene id: 79568

Gene Summary

• Gene Symbol: MAIP1   Gene   UCSC   Ensembl
• Aliases: C2orf47
• Gene name: matrix AAA peptidase interacting protein 1
• Alternate names: m-AAA protease-interacting protein 1, mitochondrial,
• Gene location: 2q33.1 (199955316: 199964116)     Exons: 7     NC_000002.12
• OMIM: 617267

Protein Summary

• Protein general information: Q8WWC4  
  • Name: m AAA protease interacting protein 1, mitochondrial (Matrix AAA peptidase interacting protein 1)
  • Length: 291  
  • Mass: 32545
• Sequence:

  MALAARLLPQFLHSRSLPCGAVRLRTPAVAEVRLPSATLCYFCRCRLGLGAALFPRSARALAASALPAQGSRWPV
  LSSPGLPAAFASFPACPQRSYSTEEKPQQHQKTKMIVLGFSNPINWVRTRIKAFLIWAYFDKEFSITEFSEGAKQ
  AFAHVSKLLSQCKFDLLEELVAKEVLHALKEKVTSLPDNHKNALAANIDEIVFTSTGDISIYYDEKGRKFVNILM
  CFWYLTSANIPSETLRGASVFQVKLGNQNVETKQLLSASYEFQREFTQGVKPDWTIARIEHSKLLE

• Structural information:
  • STRING: ENSP00000295079
• Other Databases: GeneCards:  MAIP1  Malacards:  MAIP1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007007	inner mitochondrial membrane organization	IBA	biological process
GO:0032979	protein insertion into mitochondrial inner membrane from matrix	IBA	biological process
GO:0043022	ribosome binding	IBA	molecular function
GO:0005743	mitochondrial inner membrane	IBA	cellular component
GO:0005759	mitochondrial matrix	IDA	cellular component
GO:0051560	mitochondrial calcium ion homeostasis	IMP	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0036444	calcium import into the mitochondrion	IMP	biological process
GO:0051204	protein insertion into mitochondrial membrane	IMP	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005739	mitochondrion	IEA	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0006851	mitochondrial calcium ion transmembrane transport	TAS	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005759	mitochondrial matrix	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881