|
Gene id |
7916 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
PRRC2A Gene UCSC Ensembl |
|
Aliases |
BAT2, D6S51, D6S51E, G2 |
|
Gene name |
proline rich coiled-coil 2A |
|
Alternate names |
protein PRRC2A, HLA-B-associated transcript 2, large proline-rich protein BAT2, proline-rich and coiled-coil-containing protein 2A, protein G2, |
|
Gene location |
6p21.33 (31620714: 31637779) Exons: 31 NC_000006.12
|
|
Gene summary(Entrez) |
A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated wi
|
|
OMIM |
142580 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| Coronary heart disease | GAD: 17975119 |
| Cardiovascular disease | GAD: 19023099 |
| Rheumatoid arthritis | GAD: 18835879 |
| Systemic lupus erythematosus (SLE) | GAD: 19851445 |
| Obesity | GAD: 20616199 |
| Diabetes | GAD: 19143821 |
| Non-Hodgkin lymphoma | GAD: 17827388 |
| Spontaneous abortion | GAD: 20587610 |
| Male subfertility | MIK: 28681403 |
| Male subfertility | MIK: 28681403 |
| Unexplained infertility | MIK: 25753583 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 28681403 |
Male subfe
rtility
|
Methylation |
|
78 (28 proven f
ertile males "c
ontrols," and 5
0 subfertile ma
les "cases")
|
Male infertility |
PRRC2A
ANXA2
MAPK8IP3
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|