• Gene id: 79097

Gene Summary

• Gene Symbol: TRIM48   Gene   UCSC   Ensembl
• Aliases: RNF101
• Gene name: tripartite motif containing 48
• Alternate names: tripartite motif-containing protein 48, RING finger protein 101,
• Gene location: 11q11 (55262154: 55271113)     Exons: 6     NC_000011.10
• OMIM: 609000

Protein Summary

• Protein general information: Q8IWZ4  
  • Name: Tripartite motif containing protein 48 (RING finger protein 101)
  • Length: 208  
  • Mass: 24498
• Sequence:

  MNSGISQVFQRELTCPICMNYFIDPVTIDCGHSFCRPCFYLNWQDIPILTQCFECIKTIQQRNLKTNIRLKKMAS
  LARKASLWLFLSSEEQMCGIHRETKKMFCEVDRSLLCLLCSSSQEHRYHRHCPAEWAAEEHWEKLLKKMQSLWEK
  ACENQRNLNVETTRISHWKAFGDILYRSESVLLHMPQPLNLALRAGPITGLRDRLNQF

• Structural information:
  • Interpro: IPR000315  IPR001841  IPR013083  
  • Prosite: PS50119 PS50089
  • STRING: ENSP00000402414
• Other Databases: GeneCards:  TRIM48  Malacards:  TRIM48

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0061630	ubiquitin protein ligase activity	IBA	molecular function
GO:0005737	cytoplasm	IBA	cellular component
GO:0016567	protein ubiquitination	IBA	biological process
GO:0008270	zinc ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray