• Gene id: 79050

Gene Summary

• Gene Symbol: NOC4L   Gene   UCSC   Ensembl
• Aliases: NET49, NOC4, UTP19
• Gene name: nucleolar complex associated 4 homolog
• Alternate names: nucleolar complex protein 4 homolog, NOC4 protein homolog, NOC4-like protein, nucleolar complex-associated protein 4-like protein,
• Gene location: 12q24.33 (132144420: 132152467)     Exons: 15     NC_000012.12
• OMIM: 602186

Protein Summary

• Protein general information: Q9BVI4  
  • Name: Nucleolar complex protein 4 homolog (NOC4 protein homolog) (NOC4 like protein) (Nucleolar complex associated protein 4 like protein)
  • Length: 516  
  • Mass: 58468
• Sequence:

  MEREPGAAGVRRALGRRLEAVLASRSEANAVFDILAVLQSEDQEEIQEAVRTCSRLFGALLERGELFVGQLPSEE
  MVMTGSQGATRKYKVWMRHRYHSCCNRLGELLGHPSFQVKELALSALLKFVQLEGAHPLEKSKWEGNYLFPRELF
  KLVVGGLLSPEEDQSLLLSQFREYLDYDDTRYHTMQAAVDAVARVTGQHPEVPPAFWNNAFTLLSAVSLPRREPT
  VSSFYVKRAELWDTWKVAHLKEHRRVFQAMWLSFLKHKLPLSLYKKVLLIVHDAILPQLAQPTLMIDFLTRACDL
  GGALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARL
  ALTAPPEALLMVLPFICNLLRRHPACRVLVHRPHGPELDADPYDPGEEDPAQSRALESSLWELQALQRHYHPEVS
  KAASVINQALSMPEVSIAPLLELTAYEIFERDLKKKGPEPVPLEFIPAQGLLGRPGELCAQHFTLS

• Structural information:
  • Interpro: IPR016024  IPR005612  IPR027193  
  • DIP: 32938
  • STRING: ENSP00000328854
• Other Databases: GeneCards:  NOC4L  Malacards:  NOC4L

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0030692	Noc4p-Nop14p complex	IBA	cellular component
GO:0005730	nucleolus	IBA	cellular component
GO:0032040	small-subunit processome	IBA	cellular component
GO:0042254	ribosome biogenesis	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0006364	rRNA processing	TAS	biological process
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0031965	nuclear membrane	IEA	cellular component
GO:0005730	nucleolus	IEA	cellular component
GO:0005654	nucleoplasm	IDA	cellular component
GO:0005730	nucleolus	IDA	cellular component
GO:0003723	RNA binding	HDA	molecular function
GO:0006364	rRNA processing	ISS	biological process
GO:0005730	nucleolus	ISS	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq