• Gene id: 79038

Gene Summary

• Gene Symbol: ZFYVE21   Gene   UCSC   Ensembl
• Aliases: HCVP7TP1, ZF21
• Gene name: zinc finger FYVE-type containing 21
• Alternate names: zinc finger FYVE domain-containing protein 21, FYVE domain containing 21, HCV p7-transactivated protein 1, zinc finger, FYVE domain containing 21,
• Gene location: 14q32.33 (112499756: 112463029)     Exons: 6     NC_000003.12
• OMIM: 613504

Protein Summary

• Protein general information: Q9BQ24  
  • Name: Zinc finger FYVE domain containing protein 21 (ZF21)
  • Length: 234  
  • Mass: 26506
• Sequence:

  MSSEVSARRDAKKLVRSPSGLRMVPEHRAFGSPFGLEEPQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCD
  RCCSQKVPLRRMCFVDPVRQCAECALVSLKEAEFYDKQLKVLLSGATFLVTFGNSEKPETMTCRLSNNQRYLFLD
  GDSHYEIEIVHISTVQILTEGFPPGGGNARATGMFLQYTVPGTEGVTQLKLTVVEDVTVGRRQAVAWLVAMHKAA
  KLLYESRDQ

• Structural information:
  • Interpro: IPR032031  IPR038632  IPR000306  IPR017455  IPR011011   IPR013083  
  • Prosite: PS50178
  • PDB: 2RRF
  • PDBsum: 2RRF
  • STRING: ENSP00000216602
• Other Databases: GeneCards:  ZFYVE21  Malacards:  ZFYVE21

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0046872	metal ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0031410	cytoplasmic vesicle	IEA	cellular component
GO:0005768	endosome	IEA	cellular component
GO:0030054	cell junction	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005768	endosome	IEA	cellular component
GO:0005925	focal adhesion	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)