• Gene id: 7697

Gene Summary

• Gene Symbol: ZNF138   Gene   UCSC   Ensembl
• Aliases: pHZ-32
• Gene name: zinc finger protein 138
• Alternate names: zinc finger protein 138, zinc finger protein 138 (clone pHZ-32),
• Gene location: 7q11.21 (64794427: 64860822)     Exons: 12     NC_000007.14
• OMIM: 604080

SNPs

rs761250416

Strand:    Allele origin:   Allele change:   Mutation type: delins

NC_000014.9   g.45159190dup
NC_000014.8   g.45628393dup
NG_007417.1   g.28258dup
NM_020937.4   c.1491dup
NM_020937.3   c.1491dup
NM_020937.2   c.1491dup
NM_001308133.2   c.1413dup
NM_001308133.1   c.1413dup
NM_001308134.1   c.1491dup
XM_011537035.3   c.1413dup
XM_011537  

rs144567652

Strand:    Allele origin:   Allele change:   Mutation type: snv

NC_000014.9   g.45198718C>A
NC_000014.9   g.45198718C>T
NC_000014.8   g.45667921C>A
NC_000014.8   g.45667921C>T
NG_007417.1   g.67786C>A
NG_007417.1   g.67786C>T
NM_020937.4   c.5791C>A
NM_020937.4   c.5791C>T
NM_020937.3   c.5791C>A
NM_020937.3   c.5791C>T
NM_020937.2  

Protein Summary

• Protein general information: P52744  
  • Name: Zinc finger protein 138
  • Length: 262  
  • Mass: 30592
• Sequence:

  MKRHEMVVAKHSALCSRFAQDLWLEQNIKDSFQKVTLSRYGKYGHKNLQLRKGCKSVDECKGHQGGFNGLNQCLK
  ITTSKIFQCNKYVKVMHKFSNSNRHKIRHTENKHFRCKECDKSLCMLSRLTQHKKIHTRENFYKCEECGKTFNWS
  TNLSKPKKIHTGEKPYKCEVCGKAFHQSSILTKHKIIRTGEKPYKCAHCGKAFKQSSHLTRHKIIHTEEKPYKCE
  QCGKVFKQSPTLTKHQIIYTGEEPYKCEECGKAFNLS

• Structural information:
  • Interpro: IPR036236  IPR013087  
  • Prosite: PS00028 PS50157
  • STRING: ENSP00000303533
• Other Databases: GeneCards:  ZNF138  Malacards:  ZNF138

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	molecular function
GO:0005634	nucleus	IBA	cellular component
GO:0006355	regulation of transcription, DNA-templated	IBA	biological process
GO:0046872	metal ion binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0003677	DNA binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)