|
Gene id |
7443 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
VRK1 Gene UCSC Ensembl |
|
Aliases |
PCH1, PCH1A |
|
Gene name |
VRK serine/threonine kinase 1 |
|
Alternate names |
serine/threonine-protein kinase VRK1, vaccinia related kinase 1, vaccinia virus B1R-related kinase 1, |
|
Gene location |
14q32.2 (96797381: 96881613) Exons: 15 NC_000009.12
|
|
Gene summary(Entrez) |
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal live
|
|
OMIM |
602168 |
|
| Associated diseases |
References |
| Inflammatory bowel disease | GAD: 17068223 |
| Associated with male infertility due to progressive loss of spermatogonia | MIK: 19696012 |
| Pontocerebellar hypoplasia | KEGG: H00897 |
| Spermatogenic defects | MIK: 19696012 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 19696012 |
Associated
with male
infertili
ty due to
progressiv
e loss of
spermatogo
nia
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
|