|
Gene id |
7016 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
TESK1 Gene UCSC Ensembl |
|
Gene name |
testis associated actin remodelling kinase 1 |
|
Alternate names |
dual specificity testis-specific protein kinase 1, testicular protein kinase 1, testis-specific kinase 1, |
|
Gene location |
9p13.3 (35605261: 35610032) Exons: 10 NC_000083.6
|
|
Gene summary(Entrez) |
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs).
|
|
OMIM |
601782 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| May have a role in spermatogenesis, particularly at stages of meiosis and/or early spermiogenesis | MIK: 9705840 |
| Cryptorchidism | MIK: 28606200 |
| Spermatogenetic defects | MIK: 9705840 |
| Teratozoospermia | MIK: 17327269 |
| Unexplained infertility | MIK: 25753583 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 9705840 |
May have a
role in s
permatogen
esis, part
icularly a
t stages o
f meiosis
and/or ear
ly spermio
genesis
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|