|
Gene id |
693123 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
MIR449B Gene UCSC Ensembl |
|
Aliases |
MIRN449B, mir-449b |
|
Gene name |
microRNA 449b |
|
Alternate names |
hsa-mir-449b, |
|
Gene location |
5q11.2 (55170741: 55170645) Exons: 1 NC_000005.10
|
|
Gene summary(Entrez) |
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
|
|
OMIM |
613132 |
|
| Associated diseases |
References |
| Cryptorchidism | MIK: 30103742 |
| Obstructive azoospermia | MIK: 30103742 |
| Male infertility | MIK: 30103742 |
| Oligoasthenozoospermia | MIK: 23312218 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 30103742 |
Cryptorchi
dism, Obst
ructive az
oospermia,
Male infe
rtility
|
|
|
6 (3 post-crypt
orchidopexy tes
ticular tissue
samples, 3 obst
ructive azoospe
rmia)
|
Male infertility |
Microarray microRNAs
|
Show abstract |
| 23312218 |
Oligoasthe
nozoosperm
ia
|
|
|
27 (9 normozoos
permia, 9 oligo
asthenozoosperm
ia, 9 asthenozo
ospermia)
|
Male infertility |
NGS
|
Show abstract |
|