|
Gene id |
6676 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
SPAG4 Gene UCSC Ensembl |
|
Aliases |
CT127, SUN4 |
|
Gene name |
sperm associated antigen 4 |
|
Alternate names |
sperm-associated antigen 4 protein, SUN domain-containing protein 4, Sad1 and UNC84 domain containing 4, acrosomal protein ACR55, cancer/testis antigen 127, outer dense fiber-associated protein SPAG4, sperm tail protein, |
|
Gene location |
20q11.22 (35615828: 35621093) Exons: 13 NC_000003.12
|
|
Gene summary(Entrez) |
The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece and the fibrous sheath surrounding the outer dense fibers in the principal p
|
|
OMIM |
603038 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| Globozoospermia | MIK: 26417726 |
| Globozoospermia | MIK: 26417726 |
| Male infertility | MIK: 26417726 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 26417726 |
Globozoosp
ermia with
associate
d infertil
ity
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
|