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Gene id |
6615 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
SNAI1 Gene UCSC Ensembl |
|
Aliases |
SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1 |
|
Gene name |
snail family transcriptional repressor 1 |
|
Alternate names |
zinc finger protein SNAI1, protein sna, protein snail homolog 1, snail 1 homolog, snail 1 zinc finger protein, snail family zinc finger 1, snail homolog 1, |
|
Gene location |
20q13.13 (49982979: 49988885) Exons: 3 NC_000008.11
|
|
Gene summary(Entrez) |
The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein,
|
|
OMIM |
604238 |
|
|
|
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| Associated diseases |
References |
| Head and neck cancer | GAD: 20819778 |
| Cancer (breast) | GAD: 16502042 |
| Cancer (ovarian) | GAD: 20628624 |
| Cleft defects | GAD: 20634891 |
| Spermatogenesis defects | MIK: 29381885 |
| Cryptorchidism | MIK: 28606200 |
| Male infertility | MIK: 29381885 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
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|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 29381885 |
Important
for Sperma
togenesis,
Male infe
rtility
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
|