• Gene id: 65993

Gene Summary

• Gene Symbol: MRPS34   Gene   UCSC   Ensembl
• Aliases: COXPD32, MRP-S12, MRP-S34, MRPS12
• Gene name: mitochondrial ribosomal protein S34
• Alternate names: 28S ribosomal protein S34, mitochondrial, S34mt, mitochondrial 28S ribosomal protein S34, mitochondrial small ribosomal subunit protein mS34,
• Gene location: 16p13.3 (1773133: 1771894)     Exons: 3     NC_000016.10
• Gene summary(Entrez): Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% prot
• OMIM: 164958

Protein Summary

• Protein general information: P82930  
  • Name: 28S ribosomal protein S34, mitochondrial (MRP S34) (S34mt) (Mitochondrial small ribosomal subunit protein mS34)
  • Length: 218  
  • Mass: 25650
• Sequence:

  MARKKVRPRLIAELARRVRALREQLNRPRDSQLYAVDYETLTRPFSGRRLPVRAWADVRRESRLLQLLGRLPLFG
  LGRLVTRKSWLWQHDEPCYWRLTRVRPDYTAQNLDHGKAWGILTFKGKTESEAREIEHVMYHDWRLVPKHEEEAF
  TAFTPAPEDSLASVPYPPLLRAMIIAERQKNGDTSTEEPMLNVQRIRMEPWDYPAKQEDKGRAKGTPV

• Structural information:
  • Interpro: IPR032053  
  • PDB: 3J9M 6NU2
  • PDBsum: 3J9M 6NU2
  • STRING: ENSP00000177742
• Other Databases: GeneCards:  MRPS34  Malacards:  MRPS34

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0032543	mitochondrial translation	IBA	biological process
GO:0005763	mitochondrial small ribosomal subunit	IBA	cellular component
GO:0003735	structural constituent of ribosome	IBA	molecular function
GO:0032543	mitochondrial translation	IMP	biological process
GO:0005763	mitochondrial small ribosomal subunit	ISS	cellular component
GO:0032543	mitochondrial translation	ISS	biological process
GO:0003735	structural constituent of ribosome	IMP	molecular function
GO:0003735	structural constituent of ribosome	IEA	molecular function
GO:0005739	mitochondrion	IEA	cellular component
GO:0005840	ribosome	IEA	cellular component
GO:0005739	mitochondrion	IEA	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0070125	mitochondrial translational elongation	TAS	biological process
GO:0070126	mitochondrial translational termination	TAS	biological process
GO:0005739	mitochondrion	IEA	cellular component
GO:0005739	mitochondrion	IDA	cellular component

Diseases

Associated diseases	References
Combined oxidative phosphorylation deficiency	KEGG:H00891
Combined oxidative phosphorylation deficiency	KEGG:H00891
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881