• Gene id: 65983

Gene Summary

• Gene Symbol: GRAMD2B   Gene   UCSC   Ensembl
• Aliases: GRAMD3, NS3TP2
• Gene name: GRAM domain containing 2B
• Alternate names: GRAM domain-containing protein 2B, GRAM domain containing 3, GRAM domain-containing protein 3, HCV NS3-transactivated protein 2, hepatitis C virus nonstructural protein 3-transactivating protein 2,
• Gene location: 5q23.2 (69641155: 69654473)     Exons: 5     NC_000011.10

Protein Summary

• Protein general information: Q96HH9  
  • Name: GRAM domain containing protein 2B (HCV NS3 transactivated protein 2)
  • Length: 432  
  • Mass: 47869
• Sequence:

  MTELQQDVEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDG
  ASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWI
  CFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS
  PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEA
  KPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQL
  GLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD

• Structural information:
  • Protein Domains: (110..17-)
    (/note="GRAM"-)
  • Interpro: IPR004182  IPR011993  
  • STRING: ENSP00000426120
• Other Databases: GeneCards:  GRAMD2B  Malacards:  GRAMD2B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005881	cytoplasmic microtubule	IDA	cellular component
GO:0042802	identical protein binding	IPI	molecular function
GO:0042802	identical protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)