• Gene id: 64943

Gene Summary

• Gene Symbol: NT5DC2   Gene   UCSC   Ensembl
• Gene name: 5'-nucleotidase domain containing 2
• Alternate names: 5'-nucleotidase domain-containing protein 2,
• Gene location: 3p21.1 (52535026: 52524380)     Exons: 17     NC_000003.12
• OMIM: 610068

Protein Summary

• Protein general information: Q9H857  
  • Name: 5' nucleotidase domain containing protein 2 (EC 3.1.3. )
  • Length: 520  
  • Mass: 60719
• Sequence:

  MRVESGSAQERGILLESLSTLLEKTTASHEGRAPGNRELTDLLPPEVCSLLNPAAIYANNEISLRDVEVYGFDYD
  YTLAQYADALHPEIFSTARDILIEHYKYPEGIRKYDYNPSFAIRGLHYDIQKSLLMKIDAFHYVQLGTAYRGLQP
  VPDEEVIELYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSLPEMALLSCVVDYFLGHSLEFDQAHLYKDVTDAIRD
  VHVKGLMYQWIEQDMEKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADK
  PSFFTDRRKPFRKLDEKGSLQWDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRT
  GAIIPELEREIRIINTEQYMHSLTWQQALTGLLERMQTYQDAESRQVLAAWMKERQELRCITKALFNAQFGSIFR
  TFHNPTYFSRRLVRFSDLYMASLSCLLNYRVDFTFYPRRTPLQHEAPLWMDQLCTGCMKTPFLGDMAHIR

• Structural information:
  • Interpro: IPR036412  IPR008380  IPR023214  IPR016695  
  • STRING: ENSP00000406933
• Other Databases: GeneCards:  NT5DC2  Malacards:  NT5DC2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0008253	5'-nucleotidase activity	IBA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0016787	hydrolase activity	IEA	molecular function
GO:0016311	dephosphorylation	IEA	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq