|
Gene id |
64848 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
YTHDC2 Gene UCSC Ensembl |
|
Aliases |
CAHL, hYTHDC2 |
|
Gene name |
YTH domain containing 2 |
|
Alternate names |
3'-5' RNA helicase YTHDC2, CsA-associated helicase-like protein, probable ATP-dependent RNA helicase YTHDC2, |
|
Gene location |
5q22.2 (113513682: 113595283) Exons: 32 NC_000006.12
|
|
Gene summary(Entrez) |
This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop
|
|
OMIM |
616530 |
|
| Associated diseases |
References |
| Sickle cell anemia | GAD: 21326311 |
| Spermatogenesis defects | MIK: 28809393 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Male infertility | MIK: 28809393 |
| Regulates mammalian spermatogenesis | MIK: 28809393 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 28809393 |
Regulates
mammalian
spermatoge
nesis, Mal
e infertil
ity
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|