• Gene id: 645432

Gene Summary

• Gene Symbol: ARRDC5   Gene   UCSC   Ensembl
• Gene name: arrestin domain containing 5
• Alternate names: arrestin domain-containing protein 5,
• Gene location: 19p13.3 (4915468: 4867613)     Exons: 7     NC_000019.10
• OMIM: 601768

SNPs

rs2656927

Strand:    Allele origin:   Allele change:   Mutation type: snv

NC_000019.10   g.4908263C>T
NC_000019.9   g.4908275C>T
NG_033256.2   g.10184C>T|SEQ=[C/T]|GENE=UHRF1
ARRDC5   645432

rs8103849

Strand:    Allele origin:   Allele change:   Mutation type: snv

NC_000019.10   g.4909617C>G
NC_000019.9   g.4909629C>G
NG_033256.2   g.11538C>G
NM_001048201.3   c.-49C>G
NM_001048201.2   c.-49C>G
NM_001048201.1   c.-49C>G
XM_011527942.2   c.-49C>G|SEQ=[C/G]|GENE=UHRF1
ARRDC5   645432

Protein Summary

• Protein general information: A6NEK1  
  • Name: Arrestin domain containing protein 5
  • Length: 342  
  • Mass: 38383
• Sequence:

  MGDREECLSTPQPPMSVVKSIELVLPEDRIYLAGSSIKGQVILTLNSTLVDPIVKVELVGRGYVEWSEEAGASCD
  YSRNVICNNKADYVHKTKTFPVEDNWLSAGSHTFDFHFNLPPRLPSTFTSKFGHVFYFVQASCMGREHILAKKRM
  YLLVQGTSTFHKETPFQNPLFVEAEEKVSYNCCRQGTVCLQIQMERNTFTPGEKVVFTTEINNQTSKCIKTVVFA
  LYAHIQYEGFTPSAERRSRLDSSELLRQEANTPVTRFNTTKVVSTFNLPLLLSVSSSTQDGEIMHTRYELVTTVH
  LPWSLTSLKAKVPIIITSASVDSAICQLSEDGVLPVNPDHQN

• Structural information:
  • Interpro: IPR011021  IPR014752  IPR011022  IPR014756  
  • STRING: ENSP00000371200
• Other Databases: GeneCards:  ARRDC5  Malacards:  ARRDC5

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IBA	cellular component
GO:0005886	plasma membrane	IBA	cellular component
GO:0015031	protein transport	IBA	biological process
GO:1990756	ubiquitin ligase-substrate adaptor activity	IBA	molecular function
GO:0016567	protein ubiquitination	IEA	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq