• Gene id: 642938

Gene Summary

• Gene Symbol: INSYN2A   Gene   UCSC   Ensembl
• Aliases: C10orf141, FAM196A, INSYN2
• Gene name: inhibitory synaptic factor 2A
• Alternate names: inhibitory synaptic factor 2A, family with sequence similarity 196 member A, inhibitory synaptic protein 2, protein FAM196A,
• Gene location: 10q26.2 (127196590: 127135429)     Exons: 7     NC_000010.11

Protein Summary

• Protein general information: Q6ZSG2  
  • Name: Inhibitory synaptic factor 2A (InSyn2)
  • Length: 479  
  • Mass: 52909
• Sequence:

  MVSKDTGKCILTTSESEVEPAACLALEMKYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLSSGQLGEKREA
  KPVSCRAAYRKYMTVPARRSIPNVTKSTGVQTSPDLKKCYQTFPLDRKKGNLKSLPAADPFKSQNNGFLTDAKEK
  NEAGPMEEARPCGAGRVHKTTALVFHSNQHMNTVDQPLGVNCTEPCKSPEPLSYGEAALQNSTRPPSEEPDYQLL
  GRAKQDRGRPNSEEPAPPALRRVFKTEVATVYAPALSARAPEPGLSDSAAASQWSLCPADDERRRATHLNGLQAP
  SETALACSPPMQCLSPECSEQPSQTHTPPGLGNQPSPTAVAAGEECQRIVPHTEVVDLKAQLQMMENLISSSQET
  IKVLLGVIQELEKGEAHREGLSYRTGQDTANCDTCRNSACIIYSVELDFKQQEDKLQPVLRKLHPIEETQVIPSP
  YSQETYSSTPKQKSKTESKKHGRWKLWFL

• Structural information:
  • Interpro: IPR029337  
  • STRING: ENSP00000429763
• Other Databases: GeneCards:  INSYN2A  Malacards:  INSYN2A

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0060080	inhibitory postsynaptic potential	IBA	biological process
GO:0014069	postsynaptic density	IBA	cellular component
GO:0014069	postsynaptic density	ISS	cellular component
GO:0060080	inhibitory postsynaptic potential	ISS	biological process
GO:0030054	cell junction	IEA	cellular component
GO:0045202	synapse	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0014069	postsynaptic density	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq