• Gene id: 642612

Gene Summary

• Gene Symbol: TRIM49C   Gene   UCSC   Ensembl
• Aliases: TRIM49L2
• Gene name: tripartite motif containing 49C
• Alternate names: tripartite motif-containing protein 49C, Tripartite motif-containing protein LOC642612, tripartite motif containing 49-like 2, tripartite motif-containing protein 49-like protein 2,
• Gene location: 11q14.3 (90031105: 90073545)     Exons: 0     NC_000011.10

Protein Summary

• Protein general information: P0CI26  
  • Name: Tripartite motif containing protein 49C (Tripartite motif containing protein 49 like protein 2)
  • Length: 452  
  • Mass: 52933
• Sequence:

  MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMAS
  LARKVSLWLFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHREKLLQKMQSLWEK
  ACENHRNLNVETTRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEI
  LRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHMPQPLNPELSAGPITGLRDRLNQFRVHITLHHEEANSDI
  FLYEILRSMCIGCDHQDVPYFTATPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYRKEKNQNEKIDGKE
  GLFLLGCIKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCI
  HF

• Structural information:
  • Protein Domains: (269..45-)
    (/note="B30.2/SPRY-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00548"-)
  • Interpro: IPR001870  IPR003879  IPR013320  IPR003877  IPR000315   IPR001841  IPR013083  
  • Prosite: PS50188 PS50119 PS50089
  • STRING: ENSP00000388299
• Other Databases: GeneCards:  TRIM49C  Malacards:  TRIM49C

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016567	protein ubiquitination	IBA	biological process
GO:0005737	cytoplasm	IBA	cellular component
GO:0061630	ubiquitin protein ligase activity	IBA	molecular function
GO:0008270	zinc ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)