• Gene id: 642597

Gene Summary

• Gene Symbol: AKAIN1   Gene   UCSC   Ensembl
• Aliases: C18orf42
• Gene name: A-kinase anchor inhibitor 1
• Alternate names: A-kinase anchor protein inhibitor 1, A kinase (PRKA) anchor inhibitor 1, A-kinase anchor protein C18orf42,
• Gene location: 18p11.31 (5197751: 5142910)     Exons: 3     NC_000018.10
• OMIM: 617129

Protein Summary

• Protein general information: P0CW23  
  • Name: A kinase anchor protein inhibitor 1
  • Length: 69  
  • Mass: 7848
  • Tissue specificity: Preferentially expressed in the neural tissues (PubMed
• Sequence:

  MVFAPGEKPGNEPEEVKLQNASKQIVQNAILQAVQQVSQESQRREERISDNRDHIQLGVGELTKKHEKK

• Structural information:
  • Interpro: IPR019511  
• Other Databases: GeneCards:  AKAIN1  Malacards:  AKAIN1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0051018	protein kinase A binding	IDA	molecular function
GO:0008104	protein localization	IDA	biological process
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Hypospermatogenesis	MIK: 28361989

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28361989	Hypospermatogenesis			6 (3 controls, 3 Klienfelter syndrome	Male infertility	Microarray