|
Gene id |
6257 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
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|
Gene Symbol |
RXRB Gene UCSC Ensembl |
|
Aliases |
DAUDI6, H-2RIIBP, NR2B2, RCoR-1 |
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Gene name |
retinoid X receptor beta |
|
Alternate names |
retinoic acid receptor RXR-beta, MHC class I promoter binding protein, nuclear receptor subfamily 2 group B member 2, |
|
Gene location |
6p21.32 (33200990: 33193584) Exons: 11 NC_000020.11
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|
Gene summary(Entrez) |
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptor
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|
OMIM |
180246 |
Protein Summary
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| GO accession | Term name | Evidence code | Go category |
|---|
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| Associated diseases |
References |
| Cancer (lung) | GAD: 19170196 |
| Cancer (bladder) | GAD: 19692168 |
| Cancer (prostate) | GAD: 19255064 |
| Systemic lupus erythematosus (SLE) | GAD: 19851445 |
| Diabetes | GAD: 17389020 |
| Alzheimer's disease | GAD: 19141999 |
| Schizophrenia | GAD: 11840500 |
| Spontaneous abortion | GAD: 20587610 |
| Abnormal spermatogenesis | MIK: 8557197 |
| Chronic obstructive pulmonary disease (COPD) | GAD: 19625176 |
| Wegener granulomatosis | GAD: 19223982 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Abnormal spermatogenesis | MIK: 8557197 |
| Associated with spermatogenesis and epigenetic regulation | MIK: 21674046 |
| Unexplained infertility | MIK: 25753583 |
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| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 8557197 |
Abnormal s
permatogen
esis
|
|
|
|
Male infertility |
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|