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Gene id 6228
Gene Summary    Protein Summary    Gene ontology    KEGG pathways    Diseases    PubMed    

Gene Summary

Gene Symbol RPS23   Gene   UCSC   Ensembl
Aliases BTDD, MABAS, MCINS, PAMAS, S23, uS12
Gene name ribosomal protein S23
Alternate names 40S ribosomal protein S23, homolog of yeast ribosomal protein S28, small ribosomal subunit protein uS12,
Gene location 5q14.2 (82278353: 82273319)     Exons: 4     NC_000005.10
Gene summary(Entrez) Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal pro
OMIM 603683

Protein Summary

Protein general information P62266  

Name: 40S ribosomal protein S23 (Small ribosomal subunit protein uS12)

Length: 143  Mass: 15808

Sequence MGKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLI
KNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS
Structural information
Interpro:  IPR012340  IPR006032  IPR005680  
Prosite:   PS00055
CDD:   cd03367

PDB:  
4CXG 4CXH 4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
PDBsum:   4CXG 4CXH 4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
MINT:  
STRING:   ENSP00000296674
Other Databases GeneCards:  RPS23  Malacards:  RPS23

Gene ontology

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GO accessionTerm nameEvidence codeGo category
GO:0006412 translation
IBA biological process
GO:0005840 ribosome
IBA cellular component
GO:0022627 cytosolic small ribosomal
subunit
IBA cellular component
GO:0003735 structural constituent of
ribosome
IBA molecular function
GO:0002181 cytoplasmic translation
IDA biological process
GO:0042788 polysomal ribosome
IDA cellular component
GO:0022627 cytosolic small ribosomal
subunit
IDA cellular component
GO:0006412 translation
IMP biological process
GO:0034063 stress granule assembly
IMP biological process
GO:1990145 maintenance of translatio
nal fidelity
IMP biological process
GO:0003735 structural constituent of
ribosome
IMP molecular function
GO:0005840 ribosome
IEA cellular component
GO:0006412 translation
IEA biological process
GO:0003735 structural constituent of
ribosome
IEA molecular function
GO:0015935 small ribosomal subunit
IEA cellular component
GO:0005783 endoplasmic reticulum
IEA cellular component
GO:0005840 ribosome
IEA cellular component
GO:0005737 cytoplasm
IEA cellular component
GO:0005515 protein binding
IPI molecular function
GO:0006413 translational initiation
TAS biological process
GO:0000184 nuclear-transcribed mRNA
catabolic process, nonsen
se-mediated decay
TAS biological process
GO:0005654 nucleoplasm
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0005829 cytosol
TAS cellular component
GO:0006614 SRP-dependent cotranslati
onal protein targeting to
membrane
TAS biological process
GO:0019083 viral transcription
TAS biological process
GO:0005515 protein binding
IPI molecular function
GO:0005515 protein binding
IPI molecular function
GO:0005515 protein binding
IPI molecular function
GO:0005737 cytoplasm
IEA cellular component
GO:0005791 rough endoplasmic reticul
um
IEA cellular component
GO:0005829 cytosol
IEA cellular component
GO:0005783 endoplasmic reticulum
IDA cellular component
GO:0005829 cytosol
IDA cellular component
GO:0006412 translation
IC biological process
GO:0006412 translation
IC biological process
GO:0022627 cytosolic small ribosomal
subunit
IDA cellular component
GO:0022627 cytosolic small ribosomal
subunit
HDA cellular component
GO:0016020 membrane
HDA cellular component
GO:0005840 ribosome
NAS cellular component
GO:0003723 RNA binding
HDA molecular function

KEGG pathways

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Pathway idPathway name
hsa03010Ribosome
Associated diseases References
Hypospermatogenesis MIK: 28361989
Teratozoospermia MIK: 17327269

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
17327269 Teratozoos
permia

19 (6 controls
, 13 cases)
Male infertility GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
28361989 Hyposperma
togenesis

6 (3 controls,
3 Klienfelter s
yndrome
Male infertility Microarray
Show abstract