• Gene id: 6171

Gene Summary

• Gene Symbol: RPL41   Gene   UCSC   Ensembl
• Aliases: L41
• Gene name: ribosomal protein L41
• Alternate names: 60S ribosomal protein L41, HG12 protein, homologue of yeast ribosomal protein YL41, large ribosomal subunit protein eL41,
• Gene location: 12q13.2 (56116632: 56117966)     Exons: 4     NC_000012.12
• Gene summary(Entrez): Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal pro
• OMIM: 613315

Protein Summary

• Protein general information: P62945  
  • Name: 60S ribosomal protein L41 (HG12) (Large ribosomal subunit protein eL41)
  • Length: 25  
  • Mass: 3456
• Sequence:

  MRAKWRKKRMRRLKRKRRKMRQRSK

• Structural information:
  • Interpro: IPR007836  
  • PDB: 4UG0 4V6X 5A2Q 5AJ0 5LKS 5OA3 5VYC 6EK0 6G5H 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
  • PDBsum: 4UG0 4V6X 5A2Q 5AJ0 5LKS 5OA3 5VYC 6EK0 6G5H 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
  • DIP: 46893
  • STRING: ENSP00000485567
• Other Databases: GeneCards:  RPL41  Malacards:  RPL41

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0022625	cytosolic large ribosomal subunit	IDA	cellular component
GO:0002181	cytoplasmic translation	IDA	biological process
GO:0042788	polysomal ribosome	IDA	cellular component
GO:0005840	ribosome	IEA	cellular component
GO:0006412	translation	IEA	biological process
GO:0003735	structural constituent of ribosome	IEA	molecular function
GO:0005840	ribosome	IEA	cellular component
GO:0003723	RNA binding	TAS	molecular function
GO:0003735	structural constituent of ribosome	TAS	molecular function
GO:0006412	translation	TAS	biological process
GO:0022625	cytosolic large ribosomal subunit	TAS	cellular component
GO:0006413	translational initiation	TAS	biological process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	TAS	biological process
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	TAS	biological process
GO:0019083	viral transcription	TAS	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005783	endoplasmic reticulum	IDA	cellular component
GO:0003730	mRNA 3'-UTR binding	IDA	molecular function
GO:0048027	mRNA 5'-UTR binding	IDA	molecular function
GO:0022625	cytosolic large ribosomal subunit	HDA	cellular component
GO:0006412	translation	NAS	biological process
GO:0003735	structural constituent of ribosome	NAS	molecular function

KEGG pathways

Pathway id	Pathway name
hsa03010	Ribosome

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)