• Gene id: 5926

Gene Summary

• Gene Symbol: ARID4A   Gene   UCSC   Ensembl
• Aliases: RBBP-1, RBBP1, RBP-1, RBP1
• Gene name: AT-rich interaction domain 4A
• Alternate names: AT-rich interactive domain-containing protein 4A, ARID domain-containing protein 4A, AT rich interactive domain 4A (RBP1-like), retinoblastoma-binding protein 1,
• Gene location: 14q23.1 (58298384: 58373875)     Exons: 28     NC_000010.11
• Gene summary(Entrez): The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein
• OMIM: 180201

Protein Summary

Gene ontology

GO accession	Term name	Evidence code	Go category

Diseases

Associated diseases	References
Spermatogenesis defects	MIK: 23487765
Male factor infertility	MIK: 23487765
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Regulation of sertoli cell function	MIK: 23487765
Male infertility	MIK: 23487765
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
23487765	Regulation of sertoli cell function, Male infertility				Male infertility
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881