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Gene id |
5888 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
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|
Gene Symbol |
RAD51 Gene UCSC Ensembl |
|
Aliases |
BRCC5, FANCR, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA |
|
Gene name |
RAD51 recombinase |
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Alternate names |
DNA repair protein RAD51 homolog 1, BRCA1/BRCA2-containing complex, subunit 5, RAD51 homolog A, RecA, E. coli, homolog of, RecA-like protein, recombination protein A, |
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Gene location |
15q15.1 (40694773: 40732339) Exons: 13 NC_000023.11
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|
Gene summary(Entrez) |
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This pr
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|
OMIM |
179617 |
Protein Summary
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| GO accession | Term name | Evidence code | Go category |
|---|
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| Associated diseases |
References |
| Cancer (squamous cell) | GAD: 20804747 |
| Cancer (stomach) | GAD: 16843501 |
| Cancer (lung) | GAD: 19170196 |
| Adenocarcinoma | GAD: 19690177 |
| Cancer (bladder) | GAD: 17557904 |
| Cancer (breast) | GAD: 15138485 |
| Colorectal cancer | GAD: 19606696 |
| Head and neck cancer | GAD: 17118968 |
| Leukemia | GAD: 19549356 |
| Esophageal adenocarcinoma | GAD: 20453000 |
| Cancer (ovarian) | GAD: 12883740 |
| Cancer (prostate) | GAD: 16638864 |
| Cancer (thyroid) | GAD: 19772428 |
| Fanconi anemia | KEGG: H00238 |
| Multiple sclerosis | GAD: 20522537 |
| Non-Hodgkin lymphoma | GAD: 20813000 |
| Spermatogenesis defects | MIK: 28178517 |
| Chronic obstructive pulmonary disease (COPD) | GAD: 19625176 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Spermatogenesis impairement, Male infertility | MIK: 28178517 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
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| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 28178517 |
Spermatoge
nesis impa
irement, M
ale infert
ility
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
|