• Gene id: 57710

Gene Summary

• Gene Symbol: KIAA1614   Gene   UCSC   Ensembl
• Gene name: KIAA1614
• Alternate names: uncharacterized protein KIAA1614,
• Gene location: 1q25.3 (180912896: 180951613)     Exons: 9     NC_000001.11
• OMIM: 615392

Protein Summary

• Protein general information: Q5VZ46  
  • Name: Uncharacterized protein KIAA1614
  • Length: 1190  
  • Mass: 126604
• Sequence:

  MEGTEAAAAKPAGGSPQGPKTGSGTASPVEGTSAVEWSGPEPQLDNGHPPRPWPCPQENRTSSLMAPQPPRVWGV
  QLQGPSVLESKVRALKEKMTVAKQGVSPCSASQEWSSPKKPQCRRGKAGRAGTPSEGSFLPGAVVAPRTQNLPDG
  QLDGSINEEQPARDGGPRLPRPPAPGREYCNRGSPWPPEAEWTLPDHDRGPLLGPSSLQQSPIHGVTPGRPGGPG
  HCNKIIHIPSPRTGRSYPFPDGVVTEADLDSTSLTSEEVFVPRTALLGERWRAGDLEALGAGSSVLSLSDRVERN
  RLLLQEMLNVSGQSPRKVGTPAWTPSWDTAAPERPVGDVDWASGTSLQDSGQNRTVGPNPEPVLSPRHEEATHLL
  QRARMKARTRPLRASHDIVPTITQGSRDGHRSPARDPRTTPACRDSLQNGHTSDSSSGESSGGHRPRRGPSPSHV
  RFEDESAREAEFRHLERLQQRQRQVLSTVLQAADQGPLRSKPDLADYINGAPRLRDAGQGTFHRLVGSLDRRGHP
  APPAPGSERRCQACGSCIDDPRPAQGKAPPVPRTLQELQAACGMERVLGGLSSPLRLLPAEPRLHMEWIRETHIG
  DTVCPAEVDSALDSTDNSDNCRTDSEEAGTSQAGWACGRTQGSSPRLRLRGSRPRGHRWSKKAEAELPWGLQAQQ
  HLPRADDVEVENEVKEGRGHTPEGTLFLREDAKPPDLELKRVSLGPQWQPGPGLGSHQPHPLDSRTPCRTAYATT
  APMTPESSGPGGQAQVTESHESLEIVSPSSLQQSHAEPSAPHQAWQPTASLCPEGWAPTPPPSRKTTSPVSHRKA
  ALAGLLRLGDQTEPVGIPRPPSRSAVLRTCELPPSQTQPSRPQVRHPLLALSTNNCNNSAPRGLQEPYGGAVHEG
  RVERGPCSREPEPPLENSRDGGPQGFLGSADVATINSTGITLSLSSEESESSKESEGSLQRTGSGSGGHVLSRAS
  AGAGTGPGSPSAAPLDQNKKRSSSIASTLGLKKLFSALGQSSRPKLGKSRSYSVEQLQPAPPGLTSQSRAPSLQS
  LHPVSPSHQRRKAASFQNLHSLLSSKGNRSSLYLVAGPGDHSAAGRPAKTSPRRALSVEDVGAPSLARTVGRLVE
  VFPDGTSQLQLQRSPGGTFGFCVASGNGRPDSGMPSPLPQPHGWGGLSKQGRAFWLWSEAFLVFG

• Structural information:
  • Interpro: IPR032756  
  • STRING: ENSP00000356560
• Other Databases: GeneCards:  KIAA1614  Malacards:  KIAA1614

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0060341	regulation of cellular localization	IBA	biological process
GO:0017048	Rho GTPase binding	IBA	molecular function
GO:0005938	cell cortex	IBA	cellular component
GO:0005080	protein kinase C binding	IBA	molecular function
GO:0016324	apical plasma membrane	IBA	cellular component
GO:0007163	establishment or maintenance of cell polarity	IBA	biological process
GO:0007098	centrosome cycle	IBA	biological process
GO:0005634	nucleus	IBA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray