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Gene id 57633
Gene Summary    Protein Summary    Gene ontology    Diseases    PubMed    

Gene Summary

Gene Symbol LRRN1   Gene   UCSC   Ensembl
Aliases FIGLER3, NLRR-1
Gene name leucine rich repeat neuronal 1
Alternate names leucine-rich repeat neuronal protein 1, fibronectin type III, immunoglobulin and leucine rich repeat domains 3, neuronal leucine-rich repeat protein 1,
Gene location 3p26.2 (3799430: 3849833)     Exons: 3     NC_000003.12
OMIM 617269

Protein Summary

Protein general information Q6UXK5  

Name: Leucine rich repeat neuronal protein 1 (Neuronal leucine rich repeat protein 1) (NLRR 1)

Length: 716  Mass: 80716

Sequence MARMSFVIAACQLVLGLLMTSLTESSIQNSECPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSNLSSDTQ
VLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYI
NHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGM
YLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGEL
VSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLRC
DCVIHWINSNKTNIRFMEPLSMFCAMPPEYKGHQVKEVLIQDSSEQCLPMISHDSFPNRLNVDIGTTVFLDCRAM
AEPEPEIYWVTPIGNKITVETLSDKYKLSSEGTLEISNIQIEDSGRYTCVAQNVQGADTRVATIKVNGTLLDGTQ
VLKIYVKQTESHSILVSWKVNSNVMTSNLKWSSATMKIDNPHITYTARVPVDVHEYNLTHLQPSTDYEVCLTVSN
IHQQTQKSCVNVTTKNAAFAVDISDQETSTALAAVMGSMFAVISLASIAVYFAKRFKRKNYHHSLKKYMQKTSSI
PLNELYPPLINLWEGDSEKDKDGSADTKPTQVDTSRSYYMW
Structural information
Protein Domains
(26..7-)
(/note="LRRNT-)
(371..42-)
(/note="LRRCT-)
(424..51-)
(/note="Ig-like-C2-type)
(525..61-)
(/note="Fibronectin-type-III)
(/evidence="ECO:0000255|PROSITE-ProRule:PRU00316"-)
Interpro:  IPR000483  IPR003961  IPR036116  IPR007110  IPR036179  
IPR013783  IPR013098  IPR003599  IPR003598  IPR001611  IPR003591  IPR032675  
Prosite:   PS50853 PS50835 PS51450
CDD:   cd00063
STRING:   ENSP00000314901
Other Databases GeneCards:  LRRN1  Malacards:  LRRN1

Gene ontology

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GO accessionTerm nameEvidence codeGo category
GO:0005615 extracellular space
IBA cellular component
GO:0031012 extracellular matrix
IBA cellular component
GO:0016020 membrane
IEA cellular component
GO:0016021 integral component of mem
brane
IEA cellular component
GO:0005515 protein binding
IPI molecular function
GO:0051965 positive regulation of sy
napse assembly
IEA biological process
GO:0016020 membrane
IEA cellular component
Associated diseases References
Unexplained infertility MIK: 25753583

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
25753583 Unexplaine
d infertil
ity

46 (17 fertile
men, 29 male pa
tients)
Male infertility Microarray
Show abstract