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Gene id 57106
Gene Summary    Protein Summary    Gene ontology    Diseases    PubMed    

Gene Summary

Gene Symbol NAT14   Gene   UCSC   Ensembl
Aliases KLP1
Gene name N-acetyltransferase 14 (putative)
Alternate names N-acetyltransferase 14, K562 cell-derived leucine-zipper-like protein 1, K562 cells-derived leucine-zipper-like protein 1, N-acetyltransferase 14 (GCN5-related, putative),
Gene location 19q13.42 (55485187: 55487565)     Exons: 3     NC_000019.10

Protein Summary

Protein general information Q8WUY8  

Name: N acetyltransferase 14 (EC 2.3.1. ) (K562 cell derived leucine zipper like protein 1)

Length: 206  Mass: 21650

Tissue specificity: Expressed in K-562 and HeLa cell lines and in brain. {ECO

Sequence MAPSHLSVREMREDEKPLVLEMLKAGVKDTENRVALHALTRPPALLLLAAASSGLRFVLASFALALLLPVFLAVA
AVKLGLRARWGSLPPPGGLGGPWVAVRGSGDVCGVLALAPGTNAGDGARVTRLSVSRWHRRRGVGRRLLAFAEAR
ARAWAGGMGEPRARLVVPVAVAAWGVGGMLEGCGYQAEGGWGCLGYTLVREFSKDL
Structural information
Protein Domains
(6..20-)
(/note="N-acetyltransferase-)
(/evidence="ECO:0000255|PROSITE-ProRule:PRU00532"-)
Interpro:  IPR016181  IPR000182  
Prosite:   PS51186
MINT:  
STRING:   ENSP00000205194
Other Databases GeneCards:  NAT14  Malacards:  NAT14

Gene ontology

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GO accessionTerm nameEvidence codeGo category
GO:0008080 N-acetyltransferase activ
ity
IBA molecular function
GO:0008080 N-acetyltransferase activ
ity
IEA molecular function
GO:0016740 transferase activity
IEA molecular function
GO:0016746 transferase activity, tra
nsferring acyl groups
IEA molecular function
GO:0016020 membrane
IEA cellular component
GO:0016021 integral component of mem
brane
IEA cellular component
GO:0003677 DNA binding
IEA molecular function
GO:0016020 membrane
IEA cellular component
GO:0005634 nucleus
NAS cellular component
GO:0045893 positive regulation of tr
anscription, DNA-template
d
NAS biological process
GO:0006352 DNA-templated transcripti
on, initiation
NAS biological process
Associated diseases References
Aberrant CpGs in Low Motility Sperm MIK: 21674046
Cryptorchidism MIK: 28606200
Teratozoospermia MIK: 17327269
Unexplained infertility MIK: 25753583

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
17327269 Teratozoos
permia

13 (5 controls,
8 cases)
Male infertility GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
21674046 Aberrant C
pGs in Low
Motility
Sperm

18
Male infertility GSE26881
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract
25753583 Unexplaine
d infertil
ity

46 (17 fertile
men, 29 male pa
tients)
Male infertility Microarray
Show abstract