• Gene id: 56951

Gene Summary

• Gene Symbol: C5orf15   Gene   UCSC   Ensembl
• Aliases: HTGN29, KCT2
• Gene name: chromosome 5 open reading frame 15
• Alternate names: keratinocyte-associated transmembrane protein 2, keratinocytes associated transmembrane protein 2,
• Gene location: 5q31.1 (133968624: 133955509)     Exons: 3     NC_000005.10

Protein Summary

• Protein general information: Q8NC54  
  • Name: Keratinocyte associated transmembrane protein 2
  • Length: 265  
  • Mass: 29235
  • Tissue specificity: Widely expressed. {ECO
• Sequence:

  MAAAVPKRMRGPAQAKLLPGSAIQALVGLARPLVLALLLVSAALSSVVSRTDSPSPTVLNSHISTPNVNALTHEN
  QTKPSISQISTTLPPTTSTKKSGGASVVPHPSPTPLSQEEADNNEDPSIEEEDLLMLNSSPSTAKDTLDNGDYGE
  PDYDWTTGPRDDDESDDTLEENRGYMEIEQSVKSFKMPSSNIEEEDSHFFFHLIIFAFCIAVVYITYHNKRKIFL
  LVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF

• Structural information:
  • Interpro: IPR037645  
  • STRING: ENSP00000231512
• Other Databases: GeneCards:  C5orf15  Malacards:  C5orf15

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881