|
Gene id |
56924 |
| Gene Summary Protein Summary KEGG pathways Diseases PubMed |
Gene Summary
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|
Gene Symbol |
PAK6 Gene UCSC Ensembl |
|
Aliases |
PAK5 |
|
Gene name |
p21 (RAC1) activated kinase 6 |
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Alternate names |
serine/threonine-protein kinase PAK 6, p21 protein (Cdc42/Rac)-activated kinase 6, p21(CDKN1A)-activated kinase 6, |
|
Gene location |
15q15.1 (40239062: 40277486) Exons: 25 NC_000015.10
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|
Gene summary(Entrez) |
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular pr
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|
OMIM |
608110 |
Protein Summary
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|
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| Associated diseases |
References |
| clear cell renal cell carcinoma | PMID:24715215 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Cryptorchidism | MIK: 28606200 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|