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Gene id 56681
Gene Summary    Protein Summary    Gene ontology    KEGG pathways    Diseases    PubMed    

Gene Summary
Gene Symbol SAR1A   Gene   UCSC   Ensembl
Aliases SAR1, SARA1, Sara, masra2
Gene name secretion associated Ras related GTPase 1A
Alternate names GTP-binding protein SAR1a, COPII-associated small GTPase, SAR1 gene homolog A, SAR1 homolog A, SAR1a gene homolog 1,
Gene location 10q22.1 (70170513: 70147288)     Exons: 8     NC_000010.11
OMIM 607691

Protein Summary
Protein general information Q9NR31  

Name: GTP binding protein SAR1a (COPII associated small GTPase)

Length: 198  Mass: 22367

Sequence MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFD
LGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREI
FGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID
Structural information
Interpro:  IPR027417  IPR005225  IPR006689  IPR006687  
Prosite:   PS51422

PDB:  		 2GAO
PDBsum:   2GAO

DIP:  
59790
MINT:  
STRING:   ENSP00000362339
Other Databases GeneCards:  SAR1A  Malacards:  SAR1A

Gene ontology

Expand All | Collapse All
GO accessionTerm nameEvidence codeGo category
GO:0061024 membrane organization
 IBA biological process
GO:0016050 vesicle organization
 IBA biological process
GO:0005783 endoplasmic reticulum
 IBA cellular component
GO:0003924 GTPase activity
 IBA molecular function
GO:0003400 regulation of COPII vesic
le coating
 IBA biological process
GO:0070971 endoplasmic reticulum exi
t site
 IBA cellular component
GO:0070863 positive regulation of pr
otein exit from endoplasm
ic reticulum
 IBA biological process
GO:0030127 COPII vesicle coat
 IBA cellular component
GO:0006888 endoplasmic reticulum to
Golgi vesicle-mediated tr
ansport
 IBA biological process
GO:0006886 intracellular protein tra
nsport
 IBA biological process
GO:0090110 COPII-coated vesicle carg
o loading
 IDA biological process
GO:0090110 COPII-coated vesicle carg
o loading
 IDA biological process
GO:0030127 COPII vesicle coat
 IDA cellular component
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005525 GTP binding
 IEA molecular function
GO:0006886 intracellular protein tra
nsport
 IEA biological process
GO:0005525 GTP binding
 IEA molecular function
GO:0005794 Golgi apparatus
 IEA cellular component
GO:0016192 vesicle-mediated transpor
t
 IEA biological process
GO:0005783 endoplasmic reticulum
 IEA cellular component
GO:0000166 nucleotide binding
 IEA molecular function
GO:0015031 protein transport
 IEA biological process
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005515 protein binding
 IPI molecular function
GO:0005794 Golgi apparatus
 IEA cellular component
GO:0005783 endoplasmic reticulum
 IEA cellular component
GO:0000139 Golgi membrane
 IEA cellular component
GO:0000139 Golgi membrane
 IEA cellular component

KEGG pathways

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Pathway idPathway name
hsa04141Protein processing in endoplasmic reticulum
hsa05134Legionellosis

Diseases

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Associated diseases References
Teratozoospermia MIK: 17327269

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
17327269 Teratozoos
permia
13 (5 controls,
8 cases)
 Male infertility GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
 Show abstract