Gene id |
5568 |
Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
Gene Symbol |
PRKACG Gene UCSC Ensembl |
Aliases |
BDPLT19, KAPG, PKACg |
Gene name |
protein kinase cAMP-activated catalytic subunit gamma |
Alternate names |
cAMP-dependent protein kinase catalytic subunit gamma, PKA C-gamma, protein kinase, cAMP-dependent, catalytic, gamma, protein kinase, cAMP-dependent, gamma catalytic subunit, serine(threonine) protein kinase, |
Gene location |
9q21.11 (69014112: 69012503) Exons: 1 NC_000009.12
|
Gene summary(Entrez) |
Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for
|
OMIM |
176893 |
Protein Summary
|
Protein general information
| P22612
Name: cAMP dependent protein kinase catalytic subunit gamma (PKA C gamma) (EC 2.7.11.11)
Length: 351 Mass: 40434
Tissue specificity: Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.
|
Sequence |
MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKIL NKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQ VVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWAL GVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
|
Structural information |
|
Other Databases |
GeneCards: PRKACG  Malacards: PRKACG |
|
GO accession | Term name | Evidence code | Go category |
---|
GO:0010737 |
protein kinase A signalin g
|
IBA |
biological process |
GO:0005634 |
nucleus
|
IBA |
cellular component |
GO:0004672 |
protein kinase activity
|
IEA |
molecular function |
GO:0004674 |
protein serine/threonine kinase activity
|
IEA |
molecular function |
GO:0005524 |
ATP binding
|
IEA |
molecular function |
GO:0006468 |
protein phosphorylation
|
IEA |
biological process |
GO:0016740 |
transferase activity
|
IEA |
molecular function |
GO:0016301 |
kinase activity
|
IEA |
molecular function |
GO:0016310 |
phosphorylation
|
IEA |
biological process |
GO:0005524 |
ATP binding
|
IEA |
molecular function |
GO:0004674 |
protein serine/threonine kinase activity
|
IEA |
molecular function |
GO:0000166 |
nucleotide binding
|
IEA |
molecular function |
GO:0004691 |
cAMP-dependent protein ki nase activity
|
TAS |
molecular function |
GO:0008584 |
male gonad development
|
TAS |
biological process |
GO:0007283 |
spermatogenesis
|
TAS |
biological process |
GO:0004679 |
AMP-activated protein kin ase activity
|
IEA |
molecular function |
GO:0004691 |
cAMP-dependent protein ki nase activity
|
IEA |
molecular function |
GO:0003091 |
renal water homeostasis
|
TAS |
biological process |
GO:0034380 |
high-density lipoprotein particle assembly
|
TAS |
biological process |
GO:0071377 |
cellular response to gluc agon stimulus
|
TAS |
biological process |
GO:0002223 |
stimulatory C-type lectin receptor signaling pathw ay
|
TAS |
biological process |
GO:0005654 |
nucleoplasm
|
TAS |
cellular component |
GO:0005654 |
nucleoplasm
|
TAS |
cellular component |
GO:0005829 |
cytosol
|
TAS |
cellular component |
GO:0005829 |
cytosol
|
TAS |
cellular component |
GO:0005829 |
cytosol
|
TAS |
cellular component |
GO:0005829 |
cytosol
|
TAS |
cellular component |
GO:0005829 |
cytosol
|
TAS |
cellular component |
GO:0005829 |
cytosol
|
TAS |
cellular component |
GO:0005829 |
cytosol
|
TAS |
cellular component |
GO:0005829 |
cytosol
|
TAS |
cellular component |
GO:0007596 |
blood coagulation
|
TAS |
biological process |
GO:0034199 |
activation of protein kin ase A activity
|
TAS |
biological process |
GO:0097546 |
ciliary base
|
TAS |
cellular component |
GO:0097546 |
ciliary base
|
TAS |
cellular component |
GO:0045171 |
intercellular bridge
|
IDA |
cellular component |
GO:0005829 |
cytosol
|
IDA |
cellular component |
|
|
|
|
Associated diseases |
References |
Macrothrombocytopenia | KEGG:H01740 |
Macrothrombocytopenia | KEGG:H01740 |
Teratozoospermia | MIK: 17327269 |
|
|
PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
17327269 |
Teratozoos permia
|
|
|
19 (6 controls , 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
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