• Gene id: 554235

Gene Summary

• Gene Symbol: ASPDH   Gene   UCSC   Ensembl
• Gene name: aspartate dehydrogenase domain containing
• Alternate names: putative L-aspartate dehydrogenase, aspartate dehydrogenase domain-containing protein,
• Gene location: 19q13.33 (50514683: 50511599)     Exons: 8     NC_000019.10
• OMIM: 614984

Protein Summary

• Protein general information: A6ND91  
  • Name: Putative L aspartate dehydrogenase (EC 1.4.1.21) (Aspartate dehydrogenase domain containing protein)
  • Length: 283  
  • Mass: 29946
• Sequence:

  MADRGPWRVGVVGYGRLGQSLVSRLLAQGPELGLELVFVWNRDPGRMAGSVPPSLQLQNLAALGERRPDLVVEVA
  HPKIIHESGAQILRHANLLVGSPSALSDQTTERQLLEASQHWDHAVFVARGALWGAEDIRRLDAAGGLRSLRVTM
  ATHPDGFRLEGPLAAAHSPGPCTVLYEGPVRGLCPFAPRNSNTMAAAALAAPSLGFDGVIGVLVADTSLTDMHVV
  DVELSGPRGPTGRSFAVHTRRENPAEPGAVTGSATVTAFWQSLLACCQLPSRPGIHLC

• Structural information:
  • Interpro: IPR005106  IPR002811  IPR011182  IPR036291  
  • STRING: ENSP00000373860
• Other Databases: GeneCards:  ASPDH  Malacards:  ASPDH

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0033735	aspartate dehydrogenase activity	IEA	molecular function
GO:0050661	NADP binding	IEA	molecular function
GO:0055114	oxidation-reduction process	IEA	biological process
GO:0009435	NAD biosynthetic process	IEA	biological process
GO:0016491	oxidoreductase activity	IEA	molecular function
GO:0055114	oxidation-reduction process	IEA	biological process
GO:0016491	oxidoreductase activity	IEA	molecular function
GO:0019363	pyridine nucleotide biosynthetic process	IEA	biological process
GO:0033735	aspartate dehydrogenase activity	IEA	molecular function
GO:0009435	NAD biosynthetic process	IEA	biological process

KEGG pathways

Pathway id	Pathway name
hsa01100	Metabolic pathways
hsa00760	Nicotinate and nicotinamide metabolism

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq