• Gene id: 55208

Gene Summary

• Gene Symbol: DCUN1D2   Gene   UCSC   Ensembl
• Aliases: C13orf17
• Gene name: defective in cullin neddylation 1 domain containing 2
• Alternate names: DCN1-like protein 2, DCN1, defective in cullin neddylation 1, domain containing 2, DCUN1 domain-containing protein 2, defective in cullin neddylation protein 1-like protein 2,
• Gene location: 13q34 (113492046: 113455818)     Exons: 10     NC_000013.11
• OMIM: 609221

Protein Summary

• Protein general information: Q6PH85  
  • Name: DCN1 like protein 2 (DCUN1 domain containing protein 2) (Defective in cullin neddylation protein 1 like protein 2)
  • Length: 259  
  • Mass: 30179
• Sequence:

  MHKLKSSQKDKVRQFMACTQAGERTAIYCLTQNEWRLDEATDSFFQNPDSLHRESMRNAVDKKKLERLYGRYKDP
  QDENKIGVDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSRKEFLDGMTELGCDSMEKLKALLPRLEQELKD
  TAKFKDFYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRFKFLDLWNTFLMEHHKRSIPRDTWNLLLDFGNMIAD
  DMSNYDEEGAWPVLIDDFVEYARPVVTGGKRSLF

• Structural information:
  • Protein Domains: (8..4-)
    (/note="UBA-like-)
    (60..24-)
    (/note="DCUN1-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00574"-)
  • Interpro: IPR014764  IPR042460  IPR005176  IPR009060  
  • Prosite: PS51229
  • PDB: 4GAO
  • PDBsum: 4GAO
  • DIP: 60768
  • STRING: ENSP00000417706
• Other Databases: GeneCards:  DCUN1D2  Malacards:  DCUN1D2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0000151	ubiquitin ligase complex	IBA	cellular component
GO:0032182	ubiquitin-like protein binding	IBA	molecular function
GO:0045116	protein neddylation	IBA	biological process
GO:0051443	positive regulation of ubiquitin-protein transferase activity	IBA	biological process
GO:0031624	ubiquitin conjugating enzyme binding	IBA	molecular function
GO:0097602	cullin family protein binding	IBA	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq