• Gene id: 55184

Gene Summary

• Gene Symbol: DZANK1   Gene   UCSC   Ensembl
• Aliases: ANKRD64, C20orf12, C20orf84
• Gene name: double zinc ribbon and ankyrin repeat domains 1
• Alternate names: double zinc ribbon and ankyrin repeat-containing protein 1, ankyrin repeat domain 64, ankyrin repeat-containing protein C20orf12,
• Gene location: 20p11.23 (18467184: 18383366)     Exons: 25     NC_000020.11
• Gene summary(Entrez): This gene contains two ankyrin repeat-encoding regions. Ankyrin repeats are tandemly repeated modules of about 33 amino acids described as L-shaped structures consisting of a beta-hairpin and two alpha-helices. Ankyrin repeats occur in a large number of f
• OMIM: 0

Protein Summary

• Protein general information: Q9NVP4  
  • Name: Double zinc ribbon and ankyrin repeat containing protein 1
  • Length: 752  
  • Mass: 82192
• Sequence:

  MTAGSVCVPQIIPLRVPQPGKANHEIDNNTLLEMKSDTPDVNIYYTLDGSKPEFLKRIGYGENNTFKYIKPITLP
  DGKIQVKAIAVSKDCRQSGIVTKVFHVDYEPPNIVSPEDNVENVLKDSSRQEFKNGFVGSKLKKKYKNSENQRSW
  NVNLRKFPESPLEIPAYGGGSGSRPPTRQSQSPGFAHVSGQKCLTSTEIMRIQRETDFLKCAHCLAPRPSDPFAR
  FCQECGSPVPPIFGCRLPPPEGAQMGLCAECRSLVPMNTPICVVCEAPLALQLQPQASLHLKEKVICRACGTGNP
  AHLRYCVTCEGALPSSQESMCSGDKAPPPPTQKGGTISCYRCGRWNLWEASFCGWCGAMLGIPAGCSVCPKCGAS
  NHLSARFCGSCGICVKSLVKLSLDRSLALAAEEPRPFSESLNIPLPRSDVGTKRDIGTQTVGLFYPSGKLLAKKE
  QELASQKQRQEKMSDHKPLLTAISPGRGYWRRQLDHISAHLRCYAQNNPEFRALIAEPRMGKLISATVHEDGCEV
  SIRLNYSQVSNKNLYLNKAVNFSDHLLSSAAEGDGGLCGSRSSWVSDYSQSTSDTIEKIKRIKNFKTKTFQEKKE
  QLIPENRLLLKEVGPTGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLR
  NTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSLFAAKFGQGLEDQLAQTRSLSLD
  DC

• Structural information:
  • Interpro: IPR020683  IPR036770  IPR025874  IPR026876  
  • Prosite: PS50297
  • STRING: ENSP00000262547
• Other Databases: GeneCards:  DZANK1  Malacards:  DZANK1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0046872	metal ion binding	IEA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)