• Gene id: 55015

Gene Summary

• Gene Symbol: PRPF39   Gene   UCSC   Ensembl
• Gene name: pre-mRNA processing factor 39
• Alternate names: pre-mRNA-processing factor 39, PRP39 homolog, PRP39 pre-mRNA processing factor 39 homolog,
• Gene location: 14q21.2 (45084115: 45116281)     Exons: 14     NC_000014.9
• OMIM: 114131

Protein Summary

• Protein general information: Q86UA1  
  • Name: Pre mRNA processing factor 39 (PRP39 homolog)
  • Length: 669  
  • Mass: 78430
• Sequence:

  MQNSHMDEYRNSSNGSTGNSSEVVVEHPTDFSTEIMNVTEMEQSPDDSPNVNASTEETEMASAVDLPVTLTETEA
  NFPPEYEKFWKTVENNPQDFTGWVYLLQYVEQENHLMAARKAFDRFFIHYPYCYGYWKKYADLEKRHDNIKPSDE
  VYRRGLQAIPLSVDLWIHYINFLKETLDPGDPETNNTIRGTFEHAVLAAGTDFRSDRLWEMYINWENEQGNLREV
  TAIYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELASVNGHSGDDGPPGDDLPSGIEDITDPA
  KLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRPYFHVKPLEKAQLKNWKEYLEFEIENGTHERVVVL
  FERCVISCALYEEFWIKYAKYMENHSIEGVRHVFSRACTIHLPKKPMVHMLWAAFEEQQGNINEARNILKTFEEC
  VLGLAMVRLRRVSLERRHGNLEEAEHLLQDAIKNAKSNNESSFYAVKLARHLFKIQKNLPKSRKVLLEAIERDKE
  NTKLYLNLLEMEYSGDLKQNEENILNCFDKAVHGSLPIKMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKE
  QDSLKRKAENGSEEPEEKKAHTEDTTSSSTQMIDGDLQANQAVYNYSAWYQYNYQNPWNYGQYYPPPPT

• Structural information:
  • Interpro: IPR003107  IPR011990  
  • STRING: ENSP00000348010
• Other Databases: GeneCards:  PRPF39  Malacards:  PRPF39

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0000243	commitment complex	IBA	cellular component
GO:0000395	mRNA 5'-splice site recognition	IBA	biological process
GO:0005685	U1 snRNP	IBA	cellular component
GO:0071004	U2-type prespliceosome	IBA	cellular component
GO:0006396	RNA processing	IEA	biological process
GO:0006397	mRNA processing	IEA	biological process
GO:0008380	RNA splicing	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881