• Gene id: 54838

Gene Summary

• Gene Symbol: WBP1L   Gene   UCSC   Ensembl
• Aliases: C10orf26, OPA1L, OPAL1
• Gene name: WW domain binding protein 1 like
• Alternate names: WW domain binding protein 1-like, outcome predictor in acute leukemia 1,
• Gene location: 10q24.32 (30699170: 30741408)     Exons: 34     NC_000016.10
• OMIM: 611129

Protein Summary

• Protein general information: Q9NX94  
  • Name: WW domain binding protein 1 like (Outcome predictor in acute leukemia 1)
  • Length: 342  
  • Mass: 37828
• Sequence:

  MPFLLGLRQDKEACVGTNNQSYICDTGHCCGQSQCCNYYYELWWFWLVWTIIIILSCCCVCHHRRAKHRLQAQQR
  QHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSAFQLQQQQLLPPQCGPAGGSPPGIDPT
  RGSQGAQSSPLSEPSRSSTRPPSIADPDPSDLPVDRAATKAPGMEPSGSVAGLGELDPGAFLDKDAECREELLKD
  DSSEHGAPDSKEKTPGRHRRFTGDSGIEVCVCNRGHHDDDLKEFNTLIDDALDGPLDFCDSCHVRPPGDEEEGLC
  QSSEEQAREPGHPHLPRPPACLLLNTINEQDSPNSQSSSSPS

• Structural information:
  • Interpro: IPR021684  
  • STRING: ENSP00000414721
• Other Databases: GeneCards:  WBP1L  Malacards:  WBP1L

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq