• Gene id: 54622

Gene Summary

• Gene Symbol: ARL15   Gene   UCSC   Ensembl
• Aliases: ARFRP2
• Gene name: ADP ribosylation factor like GTPase 15
• Alternate names: ADP-ribosylation factor-like protein 15, ADP-ribosylation factor-like 15, ADP-ribosylation factor-related protein 2, ARF-related protein 2,
• Gene location: 5q11.2 (54310589: 53883941)     Exons: 9     NC_000005.10
• OMIM: 0

Protein Summary

• Protein general information: Q9NXU5  
  • Name: ADP ribosylation factor like protein 15 (ADP ribosylation factor related protein 2) (ARF related protein 2)
  • Length: 204  
  • Mass: 22876
• Sequence:

  MSDLRITEAFLYMDYLCFRALCCKGPPPARPEYDLVCIGLTGSGKTSLLSKLCSESPDNVVSTTGFSIKAVPFQN
  AILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLEAARNELHSALQHPQLCTLPFLILANHQDKPAAR
  SVQEIKKYFELEPLARGKRWILQPCSLDDMDALKDSFSQLINLLEEKDHEAVRM

• Structural information:
  • Interpro: IPR042292  IPR027417  IPR006689  
  • Prosite: PS51417
  • STRING: ENSP00000433427
• Other Databases: GeneCards:  ARL15  Malacards:  ARL15

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005525	GTP binding	IEA	molecular function
GO:0005525	GTP binding	IEA	molecular function
GO:0000166	nucleotide binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0003674	molecular_function	ND	molecular function
GO:0008150	biological_process	ND	biological process
GO:0070062	extracellular exosome	HDA	cellular component
GO:0070062	extracellular exosome	HDA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq