|
Gene id |
54487 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
DGCR8 Gene UCSC Ensembl |
|
Aliases |
C22orf12, DGCRK6, Gy1, pasha |
|
Gene name |
DGCR8 microprocessor complex subunit |
|
Alternate names |
microprocessor complex subunit DGCR8, DiGeorge syndrome critical region 8, DiGeorge syndrome critical region gene 8, |
|
Gene location |
22q11.21 (20080231: 20111876) Exons: 14 NC_000011.10
|
|
Gene summary(Entrez) |
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the micr
|
|
OMIM |
609030 |
|
| Associated diseases |
References |
| Cancer (renal cell) | GAD: 19047128 |
| Cancer (lung) | GAD: 20721975 |
| Cancer (esophageal) | GAD: 19138993 |
| Head and neck cancer | GAD: 20819778 |
| Gonadal sexual differentiation | MIK: 29187591 |
| Progression of mammalian spermatogenesis and male infertility | MIK: 25244517 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Gonadal sexual differentiation | MIK: 29187591 |
| Male infertility | MIK: 29187591 |
| Progression of mammalian spermatogenesis and male infertility | MIK: 25244517 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 29187591 |
Gonadal se
xual diffe
rentiation
, Male inf
ertility
|
|
|
|
Male infertility |
|
Show abstract |
| 25244517 |
Progressio
n of mamma
lian sperm
atogenesis
and male
infertilit
y
|
|
|
|
Male infertility |
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|