• Gene id: 54442

Gene Summary

• Gene Symbol: KCTD5   Gene   UCSC   Ensembl
• Gene name: potassium channel tetramerization domain containing 5
• Alternate names: BTB/POZ domain-containing protein KCTD5, potassium channel tetramerisation domain containing 5,
• Gene location: 16p13.3 (2682522: 2709029)     Exons: 6     NC_000016.10
• OMIM: 602981

Protein Summary

• Protein general information: Q9NXV2  
  • Name: BTB/POZ domain containing protein KCTD5
  • Length: 234  
  • Mass: 26093
• Sequence:

  MAENHCELLSPARGGIGAGLGGGLCRRCSAGLGALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQ
  ADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTS
  QVPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTASEPSEKAK
  ILQERGSRM

• Structural information:
  • Protein Domains: (44..14-)
    (/note="BTB"-)
  • Interpro: IPR000210  IPR011333  IPR003131  
  • PDB: 3DRX 3DRY 3DRZ
  • PDBsum: 3DRX 3DRY 3DRZ
  • STRING: ENSP00000301738
• Other Databases: GeneCards:  KCTD5  Malacards:  KCTD5

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0031463	Cul3-RING ubiquitin ligase complex	IBA	cellular component
GO:0005737	cytoplasm	IBA	cellular component
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IBA	biological process
GO:0097602	cullin family protein binding	IBA	molecular function
GO:0005829	cytosol	IDA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0051260	protein homooligomerization	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0016032	viral process	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0044877	protein-containing complex binding	IDA	molecular function
GO:0042802	identical protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005829	cytosol	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq