|
Gene id |
53834 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
FGFRL1 Gene UCSC Ensembl |
|
Aliases |
FGFR-5, FGFR5, FHFR |
|
Gene name |
fibroblast growth factor receptor like 1 |
|
Alternate names |
fibroblast growth factor receptor-like 1, FGF homologous factor receptor, FGF receptor-like protein 1, FGFR-like protein, fibroblast growth factor receptor 5, |
|
Gene location |
4p16.3 (1009929: 1026897) Exons: 10 NC_000070.6
|
|
Gene summary(Entrez) |
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affini
|
|
OMIM |
605830 |
|
| Associated diseases |
References |
| Esophageal adenocarcinoma | GAD: 20453000 |
| 4p deletion syndrome | KEGG: H01773 |
| Asthma | GAD: 11022011 |
| Important component of germ cell-Sertoli cell and/or germ cell-germ cell communication during spermatogenesis | MIK: 8413313 |
| Cryptorchidism | MIK: 28606200 |
| Important component of germ cell-Sertoli cell and/or germ cell-germ cell communication during spermatogenesis | MIK: 8413313 |
| Teratozoospermia | MIK: 17327269 |
| Unexplained infertility | MIK: 25753583 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 8413313 |
Important
component
of germ ce
ll-Sertoli
cell and/
or germ ce
ll-germ ce
ll communi
cation dur
ing sperma
togenesis
|
|
|
|
Male infertility |
FGF4
FGFRL1
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|