• Gene id: 51646

Gene Summary

• Gene Symbol: YPEL5   Gene   UCSC   Ensembl
• Aliases: CGI-127
• Gene name: yippee like 5
• Alternate names: protein yippee-like 5,
• Gene location: 2p23.1 (30146567: 30160532)     Exons: 6     NC_000002.12
• OMIM: 0

Protein Summary

• Protein general information: P62699  
  • Name: Protein yippee like 5
  • Length: 121  
  • Mass: 13842
• Sequence:

  MGRIFLDHIGGTRLFSCANCDTILTNRSELISTRFTGATGRAFLFNKVVNLQYSEVQDRVMLTGRHMVRDVSCKN
  CNSKLGWIYEFATEDSQRYKEGRVILERALVRESEGFEEHVPSDNS

• Structural information:
  • Protein Domains: (13..11-)
    (/note="Yippee-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU01128"-)
  • Interpro: IPR034751  IPR004910  IPR039058  
  • Prosite: PS51792
  • STRING: ENSP00000368835
• Other Databases: GeneCards:  YPEL5  Malacards:  YPEL5

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0000151	ubiquitin ligase complex	IBA	cellular component
GO:0000151	ubiquitin ligase complex	IDA	cellular component
GO:0097431	mitotic spindle pole	ISS	cellular component
GO:0005813	centrosome	ISS	colocalizes with
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0030496	midbody	ISS	cellular component
GO:0005634	nucleus	ISS	cellular component
GO:0008283	cell population proliferation	ISS	biological process
GO:0046872	metal ion binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0043312	neutrophil degranulation	TAS	biological process
GO:1904724	tertiary granule lumen	TAS	cellular component
GO:1904813	ficolin-1-rich granule lumen	TAS	cellular component
GO:0005576	extracellular region	TAS	cellular component
GO:0005576	extracellular region	TAS	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0000922	spindle pole	IEA	cellular component
GO:0005815	microtubule organizing center	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0030496	midbody	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R