|
Gene id |
51533 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
PHF7 Gene UCSC Ensembl |
|
Aliases |
HSPC045, HSPC226, NYD-SP6 |
|
Gene name |
PHD finger protein 7 |
|
Alternate names |
PHD finger protein 7, testicular secretory protein Li 34, testis development protein NYD-SP6, |
|
Gene location |
3p21.1 (52410623: 52423640) Exons: 11 NC_000017.11
|
|
Gene summary(Entrez) |
Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. This gene is expressed in the testis in Sertoli cells but not
|
|
OMIM |
0 |
|
| Associated diseases |
References |
| May play a role in stimulating transcription involved in testicular development and/or spermatogenesis | MIK: 11829468 |
| Hypospermatogenesis | MIK: 28361989 |
| Male infertility | MIK: 31189663 |
| May play a role in stimulating transcription involved in testicular development and/or spermatogenesis | MIK: 11829468 |
| Non obstructive azoospermia | MIK: 23869807 |
| Sertoli cell only syndrome | MIK: 23869807 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 11829468 |
May play a
role in s
timulating
transcrip
tion invol
ved in tes
ticular de
velopment
and/or spe
rmatogenes
is
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 23869807 |
Non obstru
ctive azoo
spermia, S
ertoli cel
l only syn
drome
|
|
|
20 (4 controls,
16 cases)
|
Male infertility |
GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28361989 |
Hyposperma
togenesis
|
|
|
6 (3 controls,
3 Klienfelter s
yndrome
|
Male infertility |
Microarray
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
| 31189663 |
Male infer
tility
|
Deletion of PHF7 |
|
|
Male infertility |
|
Show abstract |
|