• Gene id: 51480

Gene Summary

• Gene Symbol: VCX2   Gene   UCSC   Ensembl
• Aliases: VCX-2r, VCX2R, VCXB
• Gene name: variable charge X-linked 2
• Alternate names: variable charge X-linked protein 2, variable charge protein on X with two repeats, variably charged protein X-B, variably charged, X chromosome 2, variably charged, X chromosome B, variably charged, X chromosome, with 2 repeats,
• Gene location: Xp22.31 (8171266: 8169943)     Exons: 3     NC_000023.11
• Gene summary(Entrez): This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes that are expressed exclusively in male germ cells. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different n
• OMIM: 300532

Protein Summary

• Protein general information: Q9H322  
  • Name: Variable charge X linked protein 2 (Variable charge protein on X with two repeats) (VCX 2r) (Variably charged protein X B) (VCX B)
  • Length: 139  
  • Mass: 14661
  • Tissue specificity: Expressed exclusively in testis.
• Sequence:

  MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPG
  PSDQPSQELPQHELPPEEPVSEGTQHDPLSQESEVEEPLSQESEVEEPLTVWMASFSPVSESTD

• Structural information:
  • Interpro: IPR026653  
  • STRING: ENSP00000321309
• Other Databases: GeneCards:  VCX2  Malacards:  VCX2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007420	brain development	IBA	biological process
GO:0005575	cellular_component	ND	cellular component
GO:0003674	molecular_function	ND	molecular function
GO:0008150	biological_process	ND	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)