• Gene id: 51118

Gene Summary

• Gene Symbol: UTP11   Gene   UCSC   Ensembl
• Aliases: CGI-94, CGI94, UTP11L
• Gene name: UTP11 small subunit processome component
• Alternate names: probable U3 small nucleolar RNA-associated protein 11, U3 snoRNA-associated protein 11, UTP11, small subunit processome component homolog, UTP11-like protein, UTP11-like, U3 small nucleolar ribonucleoprotein,
• Gene location: 1p34.3 (38012715: 38024819)     Exons: 8     NC_000001.11
• OMIM: 609440

Protein Summary

• Protein general information: Q9Y3A2  
  • Name: Probable U3 small nucleolar RNA associated protein 11 (U3 snoRNA associated protein 11) (UTP11 like protein)
  • Length: 253  
  • Mass: 30447
• Sequence:

  MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKL
  QDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFD
  VATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDL
  MDKTQKVKVKKETVNSPAIYKFQSRRKR

• Structural information:
  • Interpro: IPR007144  
  • STRING: ENSP00000362105
• Other Databases: GeneCards:  UTP11  Malacards:  UTP11

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007399	nervous system development	IMP	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0032040	small-subunit processome	IBA	cellular component
GO:0005730	nucleolus	IBA	cellular component
GO:0006364	rRNA processing	IEA	biological process
GO:0032040	small-subunit processome	IEA	cellular component
GO:0006364	rRNA processing	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0006364	rRNA processing	TAS	biological process
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005615	extracellular space	IDA	cellular component
GO:0005730	nucleolus	IDA	cellular component
GO:0005737	cytoplasm	IDA	cellular component
GO:0043065	positive regulation of apoptotic process	IMP	biological process
GO:0005730	nucleolus	IEA	cellular component
GO:0003723	RNA binding	HDA	molecular function
GO:0003723	RNA binding	HDA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)