• Gene id: 51093

Gene Summary

• Gene Symbol: RRNAD1   Gene   UCSC   Ensembl
• Aliases: C1orf66, CGI-41, METTL25B
• Gene name: ribosomal RNA adenine dimethylase domain containing 1
• Alternate names: protein RRNAD1, ribosomal RNA adenine dimethylase domain-containing protein 1,
• Gene location: 1q23.1 (156728468: 156736959)     Exons: 9     NC_000001.11
• OMIM: 613331

Protein Summary

• Protein general information: Q96FB5  
  • Name: Protein RRNAD1 (Ribosomal RNA adenine dimethylase domain containing protein 1)
  • Length: 475  
  • Mass: 52981
• Sequence:

  MPGISARGLSHEGRKQLAVNLTRVLALYRSILDAYIIEFFTDNLWDTLPCSWQEALDGLKPPQLATMLLGMPGEG
  EVVRYRSVWPLTLLALKSTACALAFTRMPGFQTPSEFLENPSQSSRLTAPFRKHVRPKKQHEIRRLGELVKKLSD
  FTGCTQVVDVGSGQGHLSRFMALGLGLMVKSIEGDQRLVERAQRLDQELLQALEKEEKRNPQVVQTSPRHSPHHV
  VRWVDPTALCEELLLPLENPCQGRARLLLTGLHACGDLSVALLRHFSCCPEVVALASVGCCYMKLSDPGGYPLSQ
  WVAGLPGYELPYRLREGACHALEEYAERLQKAGPGLRTHCYRAALETVIRRARPELRRPGVQGIPRVHELKIEEY
  VQRGLQRVGLDPQLPLNLAALQAHVAQENRVVAFFSLALLLAPLVETLILLDRLLYLQEQGFHAELLPIFSPELS
  PRNLVLVATKMPLGQALSVLETEDS

• Structural information:
  • Interpro: IPR025714  IPR020596  IPR029063  
  • STRING: ENSP00000357199
• Other Databases: GeneCards:  RRNAD1  Malacards:  RRNAD1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0031167	rRNA methylation	IEA	biological process
GO:0000154	rRNA modification	IEA	biological process
GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity	IEA	molecular function
GO:0008649	rRNA methyltransferase activity	IEA	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881