• Gene id: 51016

Gene Summary

• Gene Symbol: EMC9   Gene   UCSC   Ensembl
• Aliases: C14orf122, CGI-112, FAM158A
• Gene name: ER membrane protein complex subunit 9
• Alternate names: ER membrane protein complex subunit 9, UPF0172 protein FAM158A, family with sequence similarity 158, member A,
• Gene location: 14q12 (24142601: 24138958)     Exons: 5     NC_000014.9
• OMIM: 0

Protein Summary

• Protein general information: Q9Y3B6  
  • Name: ER membrane protein complex subunit 9 (Protein FAM158A)
  • Length: 208  
  • Mass: 23061
• Sequence:

  MGEVEISALAYVKMCLHAARYPHAAVNGLFLAPAPRSGECLCLTDCVPLFHSHLALSVMLEVALNQVDVWGAQAG
  LVVAGYYHANAAVNDQSPGPLALKIAGRIAEFFPDAVLIMLDNQKLVPQPRVPPVIVLENQGLRWVPKDKNLVMW
  RDWEESRQMVGALLEDRAHQHLVDFDCHLDDIRQDWTNQRLNTQITQWVGPTNGNGNA

• Structural information:
  • Protein Domains: (4..13-)
    (/note="MPN-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU01182"-)
  • Interpro: IPR005366  IPR037518  
  • Prosite: PS50249
  • CDD: cd08060
  • STRING: ENSP00000403210
• Other Databases: GeneCards:  EMC9  Malacards:  EMC9

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0072546	ER membrane protein complex	IBA	cellular component
GO:0072546	ER membrane protein complex	IDA	cellular component
GO:0005737	cytoplasm	IDA	cellular component
GO:0072546	ER membrane protein complex	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)